What precautions are advised for eating bitter melon?

Consuming excessive amounts of bitter melon -- several melons or 6 to 8 oz of fresh juice -- may cause mild abdominal pain or diarrhea. When bitter melon is prescribed as a therapeutic agent in diabetes, patients are told to eat one small melon or take no more than 60 ml (30 ml = 1 oz) per day. Diabetics taking hypoglycemic drugs, such as chlorpropamide, glyburide, or metformin, may need to alter the dosage of these drugs if they consume bitter melon on a daily basis.

Bitter melon should not be eaten by pregnant women because its active constituents (alpha and beta-monorcharins) have been shown to stimulate the uterus and may cause preterm labor.

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