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The hypoglycemic effect of the fresh juice of the unripe bitter melon has been confirmed in scientific studies in animals and humans. Bitter melon contains a compound known as charantin that is even more potent than the drug tolbutamide, which is often used in the treatment of diabetes to lower blood sugar levels. Bitter melon also contains an insulin-like compound referred to as polypeptide P, or vegetable insulin.
Since polypeptide P and bitter melon appear to have fewer side effects than insulin, they have been suggested as replacements for insulin in some patients. However, it may not be necessary to inject these insulin alternatives, as the oral administration of as little as 2 ozs of bitter melon juice has shown good results in clinical trials in patients with diabetes. Bitter melon has also been found to contain antiviral proteins.
Two of these proteins, which are present in the seeds, fruit, and leaves of bitter melon, have been shown to inhibit the AIDS virus in vitro (in test-tube studies). In 1996, the scientists conducting this research filed a U.S. patent on a novel protein they found and extracted from the fruit and seeds of bitter melon, which they named "MAP 30." Their patent states that MAP 30 is "useful for treating tumors and HIV infections."
MAP 30 has also demonstrated powerful antiviral activity against other viruses, including the herpes simplex virus. In addition, the ripe fruit of bitter melon has been shown to exhibit some rather profound anti-cancer effects, especially against leukemia.
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