Would suicide gene therapy solve the ‘T-cell dilemma’ of allogeneic bone marrow transplantation?

The mature T cells that acccompany hematopoietic stem cells during allogeneic bone marrow transplantation can mediate both beneficial and deleterious clinical effects. Suicide genes that metabolize inactive prodrugs into compounds highly toxic for dividing cells, should enable elimination of genetically modified activated T cells when necessary by time-controlled prodrug administration. More.

I cant really gove you an answer,but what I can give you is a way to a solution, that is you have to find the anglde that you relate to or peaks your interest. A good paper is one that people get drawn into because it reaches them ln some way.As for me WW11 to me, I think of the holocaust and the effect it had on the survivors, their families and those who stood by and did nothing until it was too late.