Can stem cell therapy treat depression in multiple sclerosis (MS)?

One of the most common symptoms of Multiple Sclerosis (MS) is depression. A new model of depression is now emerging, which is based upon the inhibition of neural stem cell growth within the hippocampal dentate gyrus. Factors such as stress-related glucocorticoids that inhibit stem cell growth also induce depression.As previously mentioned, it has been shown in animal studies that corticosterone significantly reduces the proliferation of oligodendrocyte precursors throughout the white and gray matter regions of the brain.

Since oligodendrocyte precursors play a major role in remyelination, the use of anti-inflammatory therapies may actually perpetuate depression as well as brain injury. In contrast to the use of steroids for treating MS, stem cell therapies promote the proliferation of new oligodendrocytes, with the secondary benefit of alleviating depression. Generally, depression clears within 30 days following CD34(+) stem cell transplantation.

I cant really gove you an answer,but what I can give you is a way to a solution, that is you have to find the anglde that you relate to or peaks your interest. A good paper is one that people get drawn into because it reaches them ln some way.As for me WW11 to me, I think of the holocaust and the effect it had on the survivors, their families and those who stood by and did nothing until it was too late.

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