Can Wireshark be used to change the content of packets?

At least on Unices and -like where raw sockets are used, this is not possible, since the packet is copied to userspace and you only work on that copy. Furthermore, sending a packet back through the raw socket may be considered an "outgoing" packet so that it is, in fact, not reinjected to the input path where it should be. Raw sockets were — according to the Linux manpage — designed to implement new protocols, IOW, raw sockets are an "endpoint", not a "passthrough station".

Please give Burp Suite a try. It includes a repeater that let's you modify HTTP requests.

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