How are the lungs of someone with asthma different than regular lungs?

Recent studies have shown that the smooth muscle surrounding the airways in asthmatics contains dramatically more mast cells than that of people without asthma. As with any allergic response the chemicals in the mast cells, the mediators, not only prompt spasm of the muscle itself, but increase mucus production, and draw other cells to the area, leading to an inflammatory response. These cells and the mediators lead to the increase in "twitchiness" of the airways characteristic of the asthmatic's lung.

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