How do Ace Inhibitors Work?

Ace inhibitors works by enlarging the blood vessels or dilate and as the result blood pressure get reduced. It works on a chemical called Angiotension II which contracts the blood vessels and narrowing it.

ACE inhibitors prevent the body from creating a hormone known as angiotensin II. They do this by blocking (inhibiting) a special chemical called angiotensin converting enzyme. This has a variety of effects but essentially relaxes blood vessels and helps to reduce the amount of water re-absorbed by the kidneys.

These actions help to decrease blood pressure as explained below. Your body has a number of different ways of maintaining your blood pressure, but there are two main elements. One of the major factors is the resistance of the body’s blood vessels.

If the blood vessels constrict (tighten), resistance increases. If the blood vessels dilate (relax), the resistance is lower. If you have the same amount of fluid travelling in one vessel the pressure will be higher when the vessel is constricted than when it is relaxed.

The other major factor influencing blood pressure is how much blood is pumped out of the heart. In a healthy person this depends on your heart rate (pulse) and the ... more.

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