How should I manage the adverse effects of low-dose aspirin?

€¢ People with severe dyspepsia or a history or aspirin-induced ulcers: usually aspirin can be continued with the addition of a proton pump inhibitor: • See the CKS topics on Dyspepsia - unidentified cause and Dyspepsia - proven peptic ulcer for further information. €¢ People with true hypersensitivity to aspirin (e.g. Rash, bronchospasm): switch to clopidogrel. More.

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