How was the smallpox vaccine originally developed?

During the 18th century, it was noticed that milkmaids rarely became infected by smallpox. The majority of milkmaids did, however, get a disease called "cow pox" once in their life (and never again) Edward Jenner (17 May 1749 - 26 January 1823, Berkely, Gloucestershire, England) experimented and found that by infecting a person with cow pox, they could be immunised against smallpox This immunisation is caused by the cow pox initiating the production of antibodies by the immune system, which are effective against both cow pox and the genetically related smallpox.

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