Start a program when EC2 linux instance boot?

Consider using cloud-init (if you are using Ubuntu), or a user-data start script . These will allow you to start an instance, configure it how you like (with necessary packages like mono), download your own code, and have it run as soon as the instance starts.

Vsekhar is correct, as far as I am aware, regarding what happens when the instance is restarted. In that case, a daemon is about the best that can be done.

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