What are lymph nodes and what do they have to do with breast cancer?

Lymph nodes are part of the system that helps protect the body against infection. €¢ The first lymph node that filters fluid from the breast is called the "sentinel node" because that is where breast cancer cells are likely to spread first. €¢ During a lumpectomy or mastectomy to remove a breast tumor, surgeons commonly remove the sentinel node for examination under a microscope.

€¢ Sometimes the sentinel node is examined immediately and if tumor cells are found, additional lymph nodes are removed. €¢ A more extensive microscopic examination, requiring one to two days for results, is almost always performed. If tumor cells are only found with the later microscopic examination, the patient may require a second surgery to remove the remaining lymph nodes.

"The GeneSearch BLN Assay offers a new approach to sentinel node testing," said Daniel Schultz, M.D., director of the FDA? S Center for Devices and Radiological Health. "Results of this rapid test are available while patients are on the ... more.

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