What are the requirements for using a Compounding Aseptic Containment Isolator (CACI), for Hazardous Drugs?

The surrounding space shall maintain a relative negative pressure of 0.01” water column and have a minimum of 12 air changes per hour. To achieve this negative pressure the CACI shall be in a segregated room- this room does not need to be a cleanroom. Negative pressure can be established by externally exhausting the CACI 100% to the outside.

NOTE: There is a recommendation that the exhaust from CACIs is totally vented and that surface wipe samples are done periodically to ensure containment. More.

I cant really gove you an answer,but what I can give you is a way to a solution, that is you have to find the anglde that you relate to or peaks your interest. A good paper is one that people get drawn into because it reaches them ln some way.As for me WW11 to me, I think of the holocaust and the effect it had on the survivors, their families and those who stood by and did nothing until it was too late.