What drugs are most commonly associated with drug-induced lupus (DIL)?

There is just a short list of medications for which there is DEFINITE PROOF of an association with drug-induced lupus. Procainamide (pro-can-a-mide) brand names Procan or Pronestyl used for heart rhythm abnormalities Hydralazine (hi-dral-a-zine) brand name Apresoline or Apresazide used for high blood pressure Isoniazid (i-so-nye-a-zid) brand name INH used for tuberculosis Quinidine (quin-i-dean) used for heart rhythm abnormalities Phenytoin, brand name Dilantin used for convulsive disorders (seizures). Are there other drugs that might cause DIL?

The overwhelming majority of cases of DIL are due to one of the 5 drugs mentioned earlier. There are other drugs, which might POSSIBLY be associated, but there is not yet definite proof of an association between them and drug-induced lupus. Check with your doctor to see if you are on any medication that might possibly explain your symptoms.

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