What is autonomic neuropathy?

Autonomic neuropathy is another form of nerve damage. The autonomic nervous system controls the body functions that are automatic, such as how fast or slow your heart is beating, the constriction of your blood vessels to keep your blood pressure stable as you go from lying to sitting to standing, and the rhythmic contractions of your intestine as it moves food through your digestive tract. Autonomic neuropathy means that there's damage to these nerves, and the result may be abnormal regulation of the heart, blood pressure, or intestinal function.

The most common problem is gastroparesis, meaning reduced stomach emptying. People with gastroparesis have severe acid reflux symptoms, a diminished appetite, or frequent nausea and vomiting. Some people with autonomic neuropathy have lower intestinal symptoms, such as frequent constipation or diarrhea.

Blood pressure and heart rate may not respond as they should to posture change, and some people develop what's called orthostatic hypotension, meaning a fall in blood pressure when going from lying to sitting or standing, that can lead to dizziness, lightheadedness, or fainting. These problems are sometimes difficult to manage, but medications designed to block stomach acid production, promote stomach emptying, treat constipation or diarrhea, regulate the heart rhythm, and raise the blood pressure can often be used to reduce the severity of the symptoms.

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