What is the lytic cycle?

The lytic cycle is one of the two cycles of viral reproduction, the other being the lysogenic cycle. These cycles should not, however, be seen as separate, but rather as somewhat interchangeable. The lytic cycle is typically considered the main method of viral replication (reproduction), since it results in the destruction of the infected cell The lytic cycle can be described as a three-stage process (it is also broken down into more stages, often as a six-stage process, too, however).

The Three-Stage process: Penetration To infect a cell, a virus must first enter the cell through the plasma membrane and (if present) the cell wall. Viruses do so by either attaching to a receptor on the cell's surface, or by simple mechanical force. The virus then releases its genetic material (either single- or double-stranded DNA or RNA) into the cell.In doing this, the cell is infected (and can also be targeted by the immune system) Biosynthesis The virus' nucleic acid uses the host cell's "machinery" to make large amounts of viral components.

In the case of DNA viruses, the DNA transcribes itself into messenger RNA (mRNA) molecules that are then used to direct the cell's ribosomes. One of the first polypeptides to be translated is one that destroys the hosts' DNA.In retroviruses (which inject an RNA strand), a unique enzyme called reverse transcriptase is able o transcribe the viral RNA into DNA, which is then transcribed again into mRNA Maturation and lysis After many copies of viral components are made, they are assembled into complete viruses. The phage then directs production of an enzyme that breaks down the cell wall and allows fluid to enter.

The cell eventually becomes filled with viruses (typically 100-200) and liquid, and bursts (lyses); thus giving the lytic cycle its name. The new viruses are then free to infect other cells Lytic cycle without lysis Some viruses escape the host cell without bursting the cell membrane, but rather bud off from it by taking a portion of the membrane with them. Because it otherwise is characteristic of the lytic cycle in other steps, it still belongs to this category.

Hepatitis C viruses presumably use this method The lytic cycle is one of the two cycles of viral reproduction, the other being the lysogenic cycle. These cycles should not, however, be seen as separate, but rather as somewhat interchangeable. The lytic cycle is typically considered the main method of viral replication, since it results in the destruction of the infected cell The lytic cycle is a three-stage process Penetration To infect a cell, a virus must first enter the cell through the plasma membrane and (if present) the cell wall.

Viruses do so by either attaching to a receptor on the cell's surface or by simple mechanical force. The virus then releases its genetic material (either single- or double-stranded DNA or RNA) into the cell. In doing, the cell is infected and can also be targeted by the immune system Biosynthesis.

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