What is the role of hormones in menopausal transition?

The beginning of the menopausal transition is marked by the onset of irregular menstrual cycles in women who have had regular cycles previously. The changes in a woman's periods are a signal that changes are occurring in her ovaries. The changes in your ovaries are orchestrated by a complex set of signals from hormones in the brain, pituitary gland, and ovaries themselves.

Hormones help control the chemistry of the body. Reproductive hormones control the development of follicles (or egg sacs) in the ovaries. Follicles contain eggs (ova) that develop until it is time to release one of them from the ovary.

This happens each cycle, making fertilization and implantation possible. In addition to containing ova, the follicles produce hormones, including estrogen. This is the hormone that supports the female characteristics of your bodies, such as the development of breasts and the cells lining the vagina.

The ovaries also make androgens, hormones typically associated with support of "male" bodily characteristics, such as hair distribution and muscle development.

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