Why do I produce more mucus during an asthma attack?

Normally thin and watery, mucus traps bacteria or pollen or dust or other foreign particles. The cilia lining the airways then help push the mucus up and out of the lungs. This is the so-called "mucociliary escalator."

During asthma attacks this escalator is like the escalators at the New York City subway station at 52nd Street and Lexington Avenue: It doesn't work very well. The mucus turns dry and hard, partly due to the labored breathing common in asthma attacks. It thickens as cells such as eosinophils, ciliated epithelial cells, polys, and lymphocytes die off and clog the airway.

This thick, dry mucus in turn makes it harder for cilia to push up the foreign substances, and at the same time, the cilia themselves are rendered less effective as the ciliated cells themselves die and slough off. As the airways begin to relax and breathing becomes easier, some patients begin to cough up mucus. Patients should thin this mucus as much as possible by drinking lots of fluids during an attack.

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