Why is fondaparinux contraindicated in low body weight surgery patients but not in other low weight patients?

Background According to the prescribing information for fondaparinux (Arixtra by GlaxoSmithKline), venous thromboembolism (VTE) prophylactic therapy is contraindicated in patients with a body weight of VTE prophylaxis data reviewed The ARTEMIS study was a randomized, multicenter, double-blind, placebo controlled trial that evaluated the efficacy and safety of fondaparinux for the prevention of VTE in older acutely ill medical patients expected to remain in bed for at least 4 days.2 Patients were randomized to fondaparinux 2. ... more.

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