How can I activate sirtuin to get its anti-aging benefits?

The main way sirtuin is activated is through restricting calories, but it's also done through the heat-shock mechanism as a survival mechanism. When animals are exposed to extremely hot water, sirtuin kicks in to help them survive the shock and live on. Sirtuin production can also be turned on by other things—resveratrol in red wine being a biggie, as well as quercitin in apples and onions, and physical activity.

Sirtuin may end up being the ultimate anti-ager.

I cant really gove you an answer,but what I can give you is a way to a solution, that is you have to find the anglde that you relate to or peaks your interest. A good paper is one that people get drawn into because it reaches them ln some way.As for me WW11 to me, I think of the holocaust and the effect it had on the survivors, their families and those who stood by and did nothing until it was too late.