Is initial success of thrombolytic therapy with rt-PA in patients with lower limb ischemia durable?

Geier B; Mumme A; Kster O; Marpe B; Hummel T; Asciutto G Klinik für Gefässchirurgie, St. Josef-Hospital, Klinikum der Ruhr-Universität Bochum, Germany. Bruno. [email protected] BACKGROUND: Catheter-directed intraarterial thrombolytic therapy with rt-PA has been established as an alternative to surgery in selected patients with lower limb ischemia.

The purpose of this study is to evaluate its long-term results and to try to identify patient variables influencing outcome. PATIENTS AND METHODS: The results of thrombolytic treatment for acute or subacute lower limb ischemia in 82 patients (51 male, 31 female) were retrospectively analysed. Clinical data (time of symptoms onset, clinical stage, type of affected vessel, anatomical localisation) as well as comorbidities were recorded.

The success rate of thrombolysis as well as the incidence of adverse events was evaluated. Patients with initial success were followed up after a median of 52,5 months. RESULTS: Thrombolytic therapy was successful ... more.

I cant really gove you an answer,but what I can give you is a way to a solution, that is you have to find the anglde that you relate to or peaks your interest. A good paper is one that people get drawn into because it reaches them ln some way.As for me WW11 to me, I think of the holocaust and the effect it had on the survivors, their families and those who stood by and did nothing until it was too late.