Disturbance in the Mind/Brain-Gut Connection (the connection between the central nervous system or CNS, and the enteric nervous system or ENS) leads to faulty regulation of gut motility and peristalsis, which can also result in spasm. These effects are largely mediated through the autonomic nervous system (ANS). Disturbances in motility are responsible for irritable bowel syndrome (IBS) symptoms -- abdominal pain, diarrhea, constipation or any combination of them.
However, research has shown that some of the same motility disturbances that occur with IBS can also occur in healthy people. Furthermore, IBS symptoms are not always accompanied by motility abnormalities, and motility abnormalities are not always accompanied by symptoms. There is another reason for the discomfort and pain of IBS -- increased gut sensitivity.
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