How much niacin should I take to boost my HDL cholesterol?

I recommend taking 100 milligrams of niacin four times a day to increase your (good) HDL cholesterol level. Regular (and over-the-counter) niacin is much cheaper than prescription niacin, and there seems to be a beneficial effect of extended-release doses. Sometimes higher doses are needed, in which case your doctor needs to peek at your liver function to ensure that you avoid the uncommon toxicity.

To reduce flushing (feeling hot and light-headed), take an aspirin a half hour ahead of time and take the niacin as you go to bed. Do not increase the dose above this level without talking to your doctor, and check with your doctor before using niacin at any dose if you have a history of liver problems.

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